GHK-Cu (100mg)

For Laboratory Research Use Only — Not for Human or Animal Consumption. Not for distribution. Must be 18+ to purchase. GHK-Cu (Glycyl-L-histidyl-L-lysine copper(II) complex) is a naturally occurring tripeptide-copper complex first isolated from human plasma by Dr. Loren Pickart in the early 1970s. It consists of the tripeptide GHK coordinated to a copper(II) ion. GHK-Cu is endogenously present in human plasma, saliva, and urine, with plasma concentrations declining with age — an observation that has made it a subject of sustained research interest in aging biology and tissue repair.

Mechanism of Action

GHK-Cu exerts its biological effects through several documented pathways. It stimulates collagen, elastin, and glycosaminoglycan synthesis in fibroblasts and keratinocytes. Research has documented its balanced modulation of matrix metalloproteinases (MMPs) and their tissue inhibitors (TIMPs), facilitating tissue remodeling without excessive matrix degradation. At the genomic level, GHK-Cu modulates expression of hundreds of genes — microarray analysis identified it as capable of shifting aged tissue gene expression profiles toward patterns associated with younger tissue. It also functions as an antioxidant through copper-dependent superoxide dismutase (SOD) activation and inhibition of lipid peroxidation.

Research History

GHK-Cu’s initial discovery in plasma wound healing factors led to decades of investigation in dermatology, wound biology, and aging research. Dr. Pickart’s foundational work characterized its stimulatory effects on collagen synthesis and established its activity in biological systems. Subsequent genomic research expanded understanding of its regulatory activity — microarray studies revealed GHK-Cu’s broad influence on gene expression networks related to inflammation resolution, antioxidant defense, and tissue architecture maintenance.

Active Research Areas

Ongoing research examines: genomic regulatory mechanisms and the breadth of gene expression modulation; collagen and elastin synthesis pathways in aged tissue models; antioxidant enzyme activation kinetics; interaction with growth factor signaling (EGF, FGF, VEGF); and neuroprotective activity in neuronal survival assay models.

Specifications

Formulated as a 100mg lyophilized vial for enhanced laboratory stability and reconstitution accuracy. Store sealed away from light contact. Store in a controlled climate matrix at −20°C for long-term research asset protection.

Where can I read the research on GHK-Cu?

We do not paraphrase research findings on this page. For a compound supplied for laboratory use, the primary sources are what matter, and they are public: the peer-reviewed record is indexed on PubMed, and registered clinical studies are listed on ClinicalTrials.gov. Both are maintained by the U.S. National Institutes of Health and are free to search.

How much does GHK-Cu cost?

GHK-Cu (100mg) is $49.95 per vial, in stock and available for immediate dispatch — that works out to $0.50 per mg, which is the figure worth comparing across suppliers, since headline vial prices are not comparable when vial sizes differ. There are no hidden surcharges, no payment-processor fees added at checkout, and no minimum order. Delivery is costed separately and transparently: same-day Bay Area courier from $19.95 depending on your city, or flat-rate FedEx 2Day nationwide. You can check the exact courier fee for your city before you order. Volume and institutional pricing is available for laboratories ordering in quantity — email support@sfbayareapeptides.com with your requirements.

How is GHK-Cu tested?

Every lot is independently tested by a third-party laboratory, with identity and purity confirmed by high-performance liquid chromatography (HPLC). Testing is carried out on each lot before it is released for sale.

Compounds studied alongside GHK-Cu

GHK-Cu sits in our Growth Hormone & Recovery category alongside the repair-oriented and secretagogue compounds. Laboratories working on tissue remodelling models most often pair it with BPC-157 (10mg), the other repair-focused peptide in the range. The 100mg vial is the largest peptide presentation we stock, which is why the per-milligram cost is an order of magnitude below the 10mg compounds.

Where can I buy GHK-Cu?

You can buy GHK-Cu online directly from this page. SF Bay Area Peptides is a San Francisco–based research-compound supplier shipping nationwide, and we hold stock locally rather than drop-shipping — which is why same-day delivery is possible at all. Order before 12:00 p.m. Pacific on a business day and your order qualifies for same-day courier delivery across the San Francisco Bay Area — San Francisco, Oakland, San Jose, Fremont, Sunnyvale, Santa Clara and 100+ more cities. Outside the Bay Area, orders ship FedEx 2Day in temperature-controlled packaging anywhere in the United States. See full delivery zones and pricing. Payment is by debit or credit card at checkout — see how payment works if you would like the detail before ordering. For Laboratory Research Use Only — Not for Human or Animal Consumption. Not for distribution. Must be 18+ to purchase.